GO:0051880 molecular_function G-quadruplex DNA binding
| PAG Title | GO:0051880 molecular_function G-quadruplex DNA binding |
| PAG ID | TAX027233 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | Interacting selectively and non-covalently with G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome. |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 310 |
| Information Content | Rich |
| Other IDs | GO:0051880 |
| Base PAG ID | TAX027233 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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